Reduced Th22 Cell Proportion and Prevention of Atopic Dermatitis in Infants Following Maternal Probiotic Supplementation
نویسندگان
چکیده
منابع مشابه
Human Breast Milk miRNA, Maternal Probiotic Supplementation and Atopic Dermatitis in Offspring
BACKGROUND Perinatal probiotic ingestion has been shown to prevent atopic dermatitis (AD) in infancy in a number of randomised trials. The Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT) trial involved a probiotic supplementation regime given solely to mothers in the perinatal period and demonstrated a ~40% relative risk reduction in the cumulative incidence of AD ...
متن کاملAtopic dermatitis prevention in children following maternal probiotic supplementation does not appear to be mediated by breast milk TSLP or TGF-β
BACKGROUND The Probiotics in Prevention of Allergy among Children in Trondheim (ProPACT) study, a randomised, placebo controlled trial, demonstrated that maternal supplementation with probiotic milk reduced the incidence of atopic dermatitis (AD) in infancy. The mechanisms behind this effect are incompletely understood and breast milk cytokines have been postulated as possible mediating factors...
متن کاملPrevention of atopic dermatitis
Atopic dermatitis now affects one in five children, and may progress to asthma and hay fever. In the absence of effective treatments that influence disease progression, prevention is a highly desirable goal. The evidence for most existing disease prevention strategies, such as avoidance of allergens and dietary interventions, has been unconvincing and inconsistent. Fresh approaches to preventio...
متن کاملAtopic dermatitis prevention and treatment.
Atopic dermatitis (AD) is the cause of substantial morbidity including severe pruritus and impaired personal and familial quality of life. Furthermore, the rising incidence and familial association of AD have highlighted the need for disease prevention. It is largely genetic in nature and cannot be avoided in all cases. However, low-risk prevention strategies have been attempted to reduce trigg...
متن کاملThe Effect of Probiotic Supplementation during Pregnancy and Lactation on Infantile Atopic Dermatitis
Due in part to the substantial increase in the number of cases of pediatric atopic dermatitis (AD) cases over the last three decades in the developing world [1], there is a trend towards approaching therapy for AD using natural therapies. An increasingly common question that dermatologists encounter from parents is whether or not probiotic supplementation during pregnancy and while breastfeedin...
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ژورنال
عنوان ژورنال: Pediatrics
سال: 2018
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2018-2420hh